The laboratories in Cell and Developmental Biology areas are engaged in cutting-edge research encompassing gene regulation, cancer biology, neurosystems, and reproductive system development and function. Experimental approaches include conventional and multidisciplinary tools, such as genetics, immunochemistry, transgenics, biochemistry, confocal and electron microscopy, tissue culture, genomics, and bioinformatics. Research questions are being addressed in both invertebrate and vertebrate model systems, including the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and mammalian cells. This broad range of activities provides excellent training opportunities for graduate and undergraduate students, and post-doctoral fellows.

Faculty & Areas of Interest

André Bédard – Control of cell proliferation and transformation

Ana Campos – Nervous system development and behavior in Drosophila

Juliet Daniel – Catenins and transcription factors in normal cell growth, cancer and development

Ian Dworkin – Genomic analysis of shape and sexual differences in size and shape.

Bhagwati Gupta – Nematode development and biology

Roger Jacobs – Developmental genetics and cancer genetics in Drosophila

Jonathon Stone – Computational biology, astrobiology, and population biology

Xu-Dong Zhu – Telomere maintenance and genome stability

Relevant Graduate Courses

BIOL 6H03 / Molecular Biology of Cancer

BIOL 720 / Bioinformatics

BIOL 762 / Developmental Biology

Education 750 / Principles and Practice of University Teaching

For more information on these courses, please click here

Research Highlights

· The Bedard lab has uncovered new Src-kinase interacting genes associated with human cancers

· The Campos lab has found that insulin signaling regulates feedling behavior in Drosophila

· The Daniel lab has discovered proteins that regulate Wnt pathway function in cancerous growth and metastasis

· The Gupta lab has developed novel worm microfluidics chips for neurodegeneration and drug discovery research (Rezai et al., Lab Chip)

· Using Drosophila heart as a model, the Jacobs lab has shown that integrins play important roles in cardioblast polarization

· The Stone lab has developed a computational model to explain echinoid skeleton form and growth

· Research in the Zhu lab has led to new insights into the mechanism of telomere maintenance and genome stability