Genetics & Molecular Biology
Molecular Biology is a fundamental area of investigative research in Biology that employs new technologies and experimental approaches to examine fundamental processes in all living organisms. In the course of these investigations, we use wide variety of model organisms, including mice, guinea pigs, human tissue cell cultures, the nematode species Caenorhabditis elegans, the plant Arabidopsis thaliana, model bacteria and the fruit fly Drosophila melanogaster. The research is of immediate relevance to human health in many areas including cancer, inherited genetic diseases and disease resistance, DNA repair, and neurosystem development and function. We welcome strong applicants as undergraduate researchers, graduate students and postdoctoral fellows.
André Bédard – Control of cell proliferation and transformation.
Ana Campos – Nervous system development and behavior in Drosophila.
Robin Cameron – Plant immunity and abiotic stress responses
Juliet Daniel – Catenins and transcription factors in normal cell growth, cancer and development
Ian Dworkin – Causes and consequences of context dependent effects of mutations for genetic analyses and evolutionary dynamics.
Marie Elliot – gene regulation governing microbial development and antibiotic production
Brian Golding – molecular evolution, bioinformatics and sequence analysis
Bhagwati Gupta – Nematode development and biology.
John A. Hassell – Molecular biology of cancer.
Suleiman Igdoura – Role of sialidase in human disease.
Roger Jacobs – Developmental genetics of the cardiovascular system in Drosophila.
Herb E. Schellhorn – Genomic and transcriptomic analyses of enteric bacteria
Jonathon Stone – Computational biology, astrobiology, and population biology
Xu-Dong Zhu – Telomere maintenance and genome stability
BIOL 6B03 / Plant Metabolism and Molecular Biology
BIOL 6P03 / Medical Microbiology
BIOL 6DD3 / Molecular Evolution
BIOL 709 / Special Topics in Biology
BIOL 715 / Topics in Evolutionary Genetics
BIOL 720 / Bioinformatics
BIOL 721 / Topics in Molecular Evolution
BIOL 775 / Molecular Microbiology and Microbial Genomics
Education *750 / Principles and Practices of University Teaching
For more information on these courses, please click here
· The Bedard lab has uncovered new Src-kinase interacting genes associated with human cancers
· The Campos lab has found that insulin signaling regulates feeding behavior in Drosophila
· The Daniel lab has discovered proteins that regulate Wnt pathway function in cancerous growth and metastasis
· The Gupta lab has developed novel worm microfluidics chips for neurodegeneration and drug discovery research (Rezai et al., Lab Chip)
· Using Drosophila heart as a model, the Jacobs lab has shown that integrins play important roles in cardioblast polarization
· 2.8 million dollar Ontario Research Fund awarded to Dr. Herb Schellhorn and colleagues, to fund studies identifying diagnostic genetic determinant in E. coliand other pathogens.
· 3.5 million dollar Ontario Research Fund grant awarded to Drs Weretilnyk and Cameron to use next generation sequencing to reveal the incredible stress tolerance mechanisms of the Yukon native plant Thellungiella. The long term goal is use this knowledge to improve crop stress tolerance and sustainability.
· The Stone lab has developed a computational model to explain echinoid skeleton form and growth
· The Zhu lab has discovered a number of molecular interactions important for telomere maintenance and genomic stability.