Carmel Mothersill

Title:

Professor, Canada Research Chair (Tier 1)

Office:

NRB 228

Phone:

(905) 525-9140 ext. 26227

Email:

...

Dr. Carmel Mothersill is a radiobiologist and Canada Research Chair in Environmental Radiobiology. Her interests are in the impacts of low dose and chronic radiation exposures on non-human species and on ecosystems. She is developing biomarkers which can indicate effect (harmful or beneficial) at the level of the population, community or ecosystem. Such biomarkers will hopefully be used to aid decision making about the risks of radioactive releases in environmentally sensitive areas. Many of the system level markers identified so far relate to stress responses and immune responses which can be compromised by low level radiation exposures.

Research Interests:

Genetics & Molecular Biology

1. Induction of bystander response in human glioma cells using high-energy electrons: a role for TGF-beta1.

Gow MD. Seymour CB. Ryan LA. Mothersill CE.

Radiation Research. 173(6):769-78, 2010 Jun.

2. Eco-systems biology–from the gene to the stream.

Mothersill C. Seymour C.

Mutation Research. 687(1-2):63-6, 2010 May 1.

3. Investigation of non-linear adaptive responses and split dose recovery induced by ionizing radiation in three human epithelial derived cell lines.

Ryan LA. Seymour CB. Mothersill CE.

Dose-response: A Publication of International Hormesis Society. 7(4):292-306, 2009.

4. Development of an in vitro culture method for cells and tissues from the zebra mussel (Dreissena polymorpha).

Quinn B. Costello MJ. Dorange G. Wilson JG. Mothersill C.

Cytotechnology. 59(2):121-34, 2009 Mar.

5. Communication of ionising radiation signals–a tale of two fish.

Mothersill C. Seymour C.

International Journal of Radiation Biology. 85(11):909-19, 2009 Nov.

6. Communication of radiation-induced signals in vivo between DNA repair deficient and proficient medaka (Oryzias latipes).

Mothersill C. Smith RW. Hinton TG. Aizawa K. Seymour CB.

Environmental Science & Technology. 43(9):3335-42, 2009 May 1.

7. Implications for environmental health of multiple stressors.

Mothersill C. Seymour C.

Journal of Radiological Protection. 29(2A):A21-8, 2009 Jun.

8. Gene expression and enzyme activity of mitochondrial proteins in irradiated rainbow trout (Oncorhynchus mykiss, Walbaum) tissues in vitro.

O’Dowd C. Mothersill CE. Cairns MT. Austin B. Lyng FM. McClean B. Talbot A. Murphy JE.

Radiation Research. 171(4):464-73, 2009 Apr.

9. Development of a zebrafish spleen cell line, ZSSJ, and its growth arrest by gamma irradiation and capacity to act as feeder cells.

Xing JG. El-Sweisi W. Lee LE. Collodi P. Seymour C. Mothersill C. Bols NC.

In Vitro Cellular & Developmental Biology. Animal. 45(3-4):163-74, 2009 Mar-Apr.

10. Radiation-induced adaptive response is not seen in cell lines showing a bystander effect but is seen in lines showing HRS/IRR response.

Ryan LA. Seymour CB. Joiner MC. Mothersill CE.

International Journal of Radiation Biology. 85(1):87-95, 2009 Jan.

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